National Down Syndrome Society — Donate

The National Down Syndrome Society (NDSS) works to create a world where people with Down syndrome thrive. NDSS runs advocacy events like the NYC Buddy Walk® on September 12, 2026, which has brought together the Down syndrome community since 1995. NDSS also partners with the Honolulu Marathon as an official charity and takes public stands on laws that affect people with Down syndrome.

NDSS' mission is to create a world where individuals with Down syndrome thrive. Join Team NDSS in Hawai‘i! NDSS has been chosen as an official charity partner of the Honolulu Marathon for the first time! This race welcomes over 35,000 runners from around the world for a race that includes scenery and the Aloha spirit like nowhere else. Whether you’re a first-timer or returning for another go, you’ll be part of one of the world’s most memorable marathon weekends. 2026 NYC Buddy Walk® Since 1995, the National Down Syndrome Society Buddy Walk® has been the premier advocacy event for Down syndrome in the United States. It is also the world’s most widely recognized public awareness program for the Down syndrome community. The flagship New York City Buddy Walk attracts participants from coast to coast each year. Join NDSS on Saturday, September 12, 2026! All the Latest NDSS Letter to House Appropriations Committee NDSS Partners with CoorDown to Present the International Awareness Campaign “JUST EVOLVE” National Down Syndrome Society Hosts 2026 Gala Celebrating Thriving NDSS Statement on the Charlotte Woodward Organ Transplant Discrimination Prevention Act